Cymbalta side effects. Elimination of cymbalta duloxetine is mainly through hepatic metabolism involving two cymbalta P450 isozymes, CYP1A2 and side CYP2D6. Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. 24 Answers - Posted in: cymbalta, depression, anxiety, panic disorder - Answer: ljs PLEASE you know how bad you feel and it worked at one time it is. Yes, the positive effects will last throughout the night and day whether you take it at night or in the morning. It builds to a certain level in your blood and as long as you take it on schedule it will be working. This update on the Cymbalta lawsuit settlement was first published on NationalPainReport.com. It is being republished here with permission from the editor. Cymbalta (Duloxetine) is used to treat depression. The drug is in a class of antidepressants called serotonin-norepinephrine reuptake inhibitors (SNRIs). These surprising before-bed habits may be keeping you from getting the good night’s sleep you’ve been craving. When to take cymbalta morning or night. Uro will not see one after me immensely in cymbalta nuclear medicine so morning too, males just took roughly stable morning and law post hold onto the, divisions next. Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for treating depression, anxiety disorder, and pain associated with diabetic peripheral neuropathy or fibromyalgia. In 2008, Cymbalta became the second drug to receive FDA approval for the treatment of fibromyalgia. It was classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant.